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​Adipose Tissue and Its Functions
in the Body

Historically, adipose was considered:
​​

  • An inert tissue for lipid storage

  • Cushioning for organs

 
Now, adipose is recognized as the largest endocrine organ in the body. Adipose (cells are called adipocytes):
​

  • ​Accounts for 25-30% (range 5-50%) of body weight

  • Protects underlying organs & tissues

  • Stores fat-soluble vitamins

  • Regulates whole body metabolism

    • Energy balance and thermogenesis

    • Glucose and lipid homeostasis

    • Inflammation & immunity

  • Has high tissue regenerative potential

    • Rich source of adult stem cells

    • Structural tissue for soft tissue reconstructive procedures

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Adipocytes

Current adipose uses are limited to only autologous tissue (patient and donor are the same person). Britecyte has resolved adipose tissue immunogenicity, allowing for the use of allogeneic adipose (patient and donor are different persons) without rejection.

Adipose Degeneration and Dysfunction are Linked to Many Diseases
Dysfunctional adipose:​

  • Metabolic syndrome

  • Type 2 and 3 diabetes

  • Fatty liver disease & liver fibrosis

  • Cardiovascular diseases

  • Stroke​

Degenerated adipose:​​

  • Lipoatrophy

  • Fat pad atrophy of the foot leading to pain and plantar ulcers

  • Lipodermatosclerosis leading to venous leg ulcers

  • Congenital diseases and trauma leading to facial and body deformities

  • Aging affecting aesthetic appearance

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