Therapeutic Potential
of Adipose Tissue
Adipose (Fat) Tissue and Its Functions in the Body
Current adipose uses are limited to only autologous tissue (patient and donor are the same person).
Britecyte has resolved adipose tissue immunogenicity, allowing for the use of allogeneic adipose (patient and donor are different persons) without rejection.
Historically, adipose was considered:
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An inert tissue for lipid storage
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Cushioning for organs
Now, adipose is recognized as:
The largest endocrine organ in the body
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Accounts for 25-30% (range 5-50%) of body weight
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Protects underlying organs & tissues
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Stores fat-soluble vitamins
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Adipose cells are called “adipocytes”
That regulates whole body metabolism
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Energy balance and thermogenesis
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Glucose and lipid homeostasis
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Inflammation & immunity
With high tissue regenerative potential
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Rich source of adult stem cells
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Structural tissue for soft tissue reconstructive procedures
Adipose degeneration and/or dysfunction are linked to many diseases:
Dysfunctional adipose:
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Metabolic syndrome, type 2 and 3 diabetes, fatty liver disease, cardiovascular diseases, lipoatrophy, stroke
Degenerated adipose:
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Fat pad atrophy of the foot leading to pain, ulcerations and disabilities, body deformities affecting aesthesis and functionality